After treatment of the three effects,the particle size can be evenly below 100nm, the broken rate is more than 95%, it can be used for the treatment of fermentation tank samples and design, mainly used for biological engineering laboratories, pharmaceutical companies such as the scale of processing Escherichia coli and yeast samples,

It is standard equipment in the development and production of biological engineering and bio pharmaceutical industry , can be used for dairy products, food and beverage, fruit juice, chemical and biological industry of emulsification, homogenate, homogenization treatment.

This machine has a built-in cooling circulation system. It directly cools the homogeneous head. All the materials and pipes which contact the sample are made of 316L stainless steel.

It is optional to buy two stage homogeneous modules, and can choose to buy different homogeneous valve for different applications.

High Pressure Homogenizer Series is exclusively designed for processing the samples within fermentation tank.It is mainly used to crush the germs of E.coli and yeast for bio-engineering laboratories, pharmaceutical companies in which the samples are processed on a scale.

It can also be used in chemical and materials’ industry for emulsification and homogenization. The machine bears the characteristics of high pressure, small volume, easy operation, high processing efficiency and large amounts of samples due to using the key components imported

Main Technical Parameters：

Common problem

The oil temperature in the crankcase is too high or the main bearing temperature is too high and the treatment method

cause of issue

1) Serious oil shortage or deterioration of lubricating oil in the crankcase;

2) The bearing assembly clearance is too small or burnt;

3) The main bearing is seriously worn;

4) The lubricating oil in the crankcase is too dirty, and the bearing enters debris.

Troubleshooting method

1) Check the cause of lack of oil in the crankcase. If the oil leakage is to be tightened in time, if the main drive shaft leaks, replace the main drive shaft and bushing in time to eliminate oil leakage and add new oil or replace. New oil

2) Adjust the bearing assembly clearance or replace the bearing bush;

3) Replace the main bearing;

4) Replace with new oil or bearings.

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※The maximum working pressure 1800bar / 180Mpa / 26100psi pressure adjustable

※The maximum design pressure is 2070bar / 207Mpa / 30015psi

※Maximum processing capacity 15 L / H (250ml / min)

※The minimum volume processing capacity of 15ml

※Material residue 0ml (no residue)

※Motor power 3.0Kw / 380V / 50Hz

※Overall dimensions L1070mm * W340 mm* H460mm

※Weight <60KG

※Maximum feed particles & lt; 100 microns

※Flow control Inverter control, adjustable flow and flow adjustable

※Pressure, temperature sensors using the German brand pressure sensor optional thermostat bath

※Built-in cooler configuration cooler, do not consume materials, control homogeneous temperature

※No need to exhaust exhaust

※PLC touch screen

※Using PLC control and 7-inch touch screen operation

※ Historical data storage, query

※With temperature alarm and automatic protection

※System high pressure and operating temperature are one digital

※Real-time pressure and temperature curve display

※Has the operation permission limit function

※Electric control drive part of Japan’s Matsushita servo motor

※Condensate water connection plate with condensate access dis

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The high-pressure homogenizer is also called “high-pressure fluid nano-homogenizer”, which can make the material in the suspended state flow under high pressure and flow through the cavity with special internal structure (high-pressure homogenizing cavity) to make the material occur. A series of changes in physical, chemical, and structural properties ultimately achieve a homogeneous effect.

“High-pressure fluid nano-homogenizer” is mainly used in the fields of biology, medicine, food, chemical industry, etc., cell breakage, beverage homogenization, fine chemicals, preparation of liposome, fat emulsion, nanosuspension, microemulsion, lipid micro Balls, emulsions, dairy products, large infusions, dyes, solar panel coatings, conductive coatings, etc.

Characteristics

1. The plunger horizontal movement structure is used, and the plunger is sprayed with cooling water compared with the vertical (upper and lower) movement of the plunger, thereby prolonging the life of the plunger seal.

2. After the material leaks, it will not enter the fuel tank and will not pollute the external working environment.

3. The lubricating oil in the transmission box part can effectively make the connecting rod, crosshead, etc. smooth, and there is no trouble that the traditional type equipment needs to add grease before starting each time.

4. the overall shape of the cube, stainless steel cover, beautiful and easy to operate.

5. only one liter of material can be used for experimentation.

Main Technical Parameters：

Classification of high pressure homogenizers:

According to the structure type, it is divided into a vertical integral homogenizer and a horizontal combined homogenizer. The former is generally suitable for small and medium-sized equipment (power below 45kw); the latter is suitable for large equipment (power is above 45kw). At present, most domestic manufacturers produce vertical integral homogenizers. This type of compact structure has a beautiful appearance and a small footprint.

According to the control mode, it can be divided into manual control type, manual adjustment hydraulic control type and fully automatic control type. Currently, manual control is dominant in the market. If the entire production line is automatically controlled, a fully automatic control homogenizer can be used.

Analysis and discussion of material stratification

After using the homogenizer, the material is stratified. Let us now analyze the reasons for the stratification. When the material is placed in a liquid, the density of the liquid and the density of the material placed determine the ups and downs of the material. If the density of the material is greater than the liquid, it sinks, and if it is smaller than the liquid, it floats. Under the action of gravity, the solid particles or droplets in the liquid medium finally obtain a stable velocity, which is called the sedimentation velocity. The sedimentation velocity is determined by the following physical quantities: particle diameter straight d particle density ρp density of the medium liquid ρp viscosity of the medium liquid η Gravity acceleration g (9.8m/s)

If these magnitudes are known, the sedimentation velocity (V g) of the particles or droplets can be calculated using the following formula: (Stokes’ Law)

The above equation tells us the sedimentation velocity of particles or droplets.

● The sedimentation velocity increases with the square of the particle diameter, which means that the 5 μm particles (5*5=25) are 25 times faster than the 1 μm particles (1*1=1).

● The settling velocity increases as the density difference of the material increases.

● The settling velocity increases as the viscosity of the material and medium decreases.

● 18 is a constant

● Gravity acceleration g is 9.8m/s. From the above analysis: The high-pressure homogenizer can break the particles below 2μm or less than 1μm. The particle diameter is squared with the sedimentation velocity, so the particle size is the sedimentation velocity. The essential.

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Application

Homogenizers are mainly used for tissue dispersion in the field of biotechnology, sample preparation in the pharmaceutical industry, enzymatic treatment in the food industry, pesticide residues in foods and veterinary drug residues, as well as in the pharmaceutical, cosmetic, paint and petrochemical industries.

Advantage

1. Better stability

2. Improved preservation quality

3. Improved homogeneity

4. Better absorption quality

Main Technical Parameters：

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The Scientz-207A ultra-high pressure homogenizer utilizes the high-pressure energy generated by the servo motor to instantaneously release the material, and under the conditions of high shear, cavitation and collision effects, and dispersion effect, the material is broken, homogenized and emulsified under constant pressure working conditions.

The particle size of the material can be uniformly refined to below 100 nm, and the breaking rate can reach 95% or more.

The machine has a built-in cooling circulation system that directly cools the homogenizer. All materials in contact with the material tube are 316L stainless steel. And optional homogenizing valve. Has applied for invention patents and utility model patents.

Technical Parameters

■The maximum working pressure 1800bar / 180Mpa / 26100psi pressure adjustable

■The maximum design pressure is 2070bar / 207Mpa / 30015psi

■Maximum processing capacity 15 L / H (250ml / min)

■The minimum volume processing capacity of 15ml

■Material residue 0ml (no residue)

■Motor power 3.0Kw / 380V / 50Hz

■Overall dimensions L1070mm * W340 mm* H460mm

■Weight <60KG

■Maximum feed particles & lt; 100 microns

■Flow control Inverter control, adjustable flow and flow adjustable

■Pressure, temperature sensors using the German brand pressure sensor optional thermostat bath

■Built-in cooler configuration cooler, do not consume materials, control homogeneous temperature

■No need to exhaust exhaust

■PLC touch screen

■Using PLC control and 7-inch touch screen operation

■ Historical data storage, query

■With temperature alarm and automatic protection

■System high pressure and operating temperature are one digital

■Real-time pressure and temperature curve display

■Has the operation permission limit function

■Electric control drive part of Japan’s Matsushita servo motor

■Condensate water connection plate with condensate access dis

Applications

Ganoderma lucidum spores have a wall breaking rate of about 95%

Ganoderma lucidum spores before breaking                            Ganoderma lucidum spores after breaking

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The structure of the Scientz-150 high-pressure homogenizer is driven by a motor to generate pressure in the homogenized valve body.

The cell slurry enters the homogenizing valve body through the check valve, forcing it to rush out at high speed in the small hole of the homogenizing valve under high pressure, and due to instantaneous decompression and high-speed impact,

The cells are simultaneously disrupted by high liquid shearing effects, cavitation effects, and impact effects.

Main Technical Parameters：

The high-pressure homogenizer mainly relies on three repeatedly moving plungers to generate a great pressure. The first and second homogenizing valves are homogenized and emulsified, and the materials are discharged from the discharge port to make the materials more delicate and not stratified.

The main functions are: improve the uniformity and stability of the product; increase the shelf life; reduce the reaction time to save a lot of catalysts or additives; change the consistency of the product to improve the taste and color of the product.

Biological application case:

Enzyme engineering, human vaccine, veterinary vaccine, HPV vaccine, fusion protein, nucleic acid, insulin, reagent, antibody, etc.

Numerous biological products factories, pharmaceutical factories, universities, research institutes, E. coli, yeast, or ocean baths

Cell-like cells, etc., placed in a high-pressure homogenizer, pressurized to 1500-2000 bar, the cell wall is broken, and the cells are extracted.

The active ingredients such as proteins and enzymes have been produced into vaccines, reagents, and antibodies, which have brought considerable profits.

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Nano-pharmaceutical applications (e.g., lipid emulsions, liposomes, lipid nanoparticles, nano-suspensions)

Laboratory and large-scale processing of fermentation samples (E. coli, yeast, etc.) in bioengineering, pharmaceutical R&D, and botanical extraction

Emulsification and homogenization in food & beverage (dairy, fruit juices), pharmaceuticals, and biotechnology industries

◣Core Advantages

Built-in cooling circulation system for direct homogenizing head temperature control

316L stainless steel contact parts with mirror-polished pipelines to prevent sample residue, complying with food and pharmaceutical industry standards

Optional homogenizing valves for customized processing needs

Compact design, lightweight construction, intuitive operation, high efficiency, and large sample throughput

Patented technology (invention patent and utility model patent approved)

◣Key Features

Adjustable homogenizing pressure (0–207 MPa) to meet nano-pharmaceutical requirements

Minimum sample processing volume: 15 ml

Key components imported from Germany and Japan for extended service life

Japanese-imported servo motor for stable, reliable performance and long durability

Automatic feeding and continuous operation without the need for exhaust

Physical homogenization method with zero sample residue

Specialized tool for seal replacement, ensuring easy maintenance

User-friendly operation, convenient after-sales service, and high cost-effectiveness

PLC control system with 7-inch touch screen for intuitive operation

Historical data storage and query functionality

Temperature alarm and automatic protection mechanisms

Digital display of system pressure and operating temperature

Real-time pressure and temperature curve visualization

Operation permission restriction for data security

◣Main Technical Parameters

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High-pressure homogenizer is one of the most effective production equipment for the preparation of nano-materials by nanotechnology. Its application field is very wide, and the market demand of nearly 10 billion RMB worldwide.

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Working principle: 

The precision fit of the rotor and the stator, the working head (manufactured by the rotor and stator forgings), the claw structure, two-way suction, high shear efficiency.

Intermittent high-shear dispersion emulsifier homogenizer is a high-speed, strong circumferential tangential speed, angular velocity and other comprehensive kinetic energy through high-speed and stable rotation of the rotor.

Effectiveness; under the action of the stator, a strong, reciprocating hydraulic shear, friction, centrifugal extrusion, liquid flow collision and other comprehensive effects are formed in the gaps of the stator and the rotor, and the material is reciprocated in the container. Get the product.

Main Technical Parameters：

Main components of high pressure homogenizer

The high-pressure homogenizer is mainly composed of transmission parts (motor and electric control device, drive shaft, pulley, gear, crankshaft, connecting rod, slider, etc.); pump body part (pump body, plunger, suction valve, pressure material valve, Valve seat, etc.); homogenized part (first-level homogenizing valve body, second-level homogenizing valve body, homogenizing rod, homogenizing seat, butterfly-shaped shrapnel group, pressure regulating handle); pressure gauge part (seismic pressure gauge, The pressure gauge seat, etc.) is composed of 4 major components.

Electrical schematic of high pressure homogenizer

DZ:Automatic air switch   RD₁:Insurance  RD₂:Insurance  TQ:stop button  QA:start up button        C:AC contactor   RJ:thermal relay  D:electric motor

High pressure homogenizer can not start and solve

Cause of issue 

1) No 380V power input or phase loss; Figure 1 Electrical schematic of high voltage homogenizer

2) Insurance RD blow or air automatic switch trip;

3) The AC contactor coil is damaged or the wiring is disconnected;

4) The stop button or start button is damaged or the wire is disconnected;

5) The thermal relay is damaged;

6) The motor is damaged.

Troubleshooting method

1) Connect the 380V power supply or find out the cause of the missing phase and add it to the exclusion;

2) Replace the RD and close the air switch;

3) Replace the AC contactor coil or restore the wiring;

4) Replace the stop button, start button or restore the wiring;

5) Replace the thermal relay;

6) Repair the motor.

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