Dissolution
Refers to the rate and extent to which active pharmaceutical ingredients are dissolved from a formulation such as a tablet, capsule or granule under specified conditions. It is an indicator for evaluating the quality of oral solid preparations of drugs, and is an in vitro simple test method for simulating disintegration and dissolution of oral solid preparations in the gastrointestinal tract.
Dissolution assay
Place a certain amount of a certain preparation in the basket (dissolution cup) of the dissolution apparatus, operate at a constant temperature of 37 ° C ± 0.5 ° C, operate at a specified speed and dissolution medium, sample and determine the dissolution within a specified time. the amount.
